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Doxycycline Hyclate

Doxycycline Hyclate

Doxycycline hyclate CAS number: 24390-14-5 Molecular formula: C22H24N2O8.HCL.1/2C2H5OH.1/2H2O Molecular weight: 512.9 Chemical Structure: ...

Doxycycline hyclate

CAS number: 24390-14-5 

Molecular formula: C22H24N2O8.HCL.1/2C2H5OH.1/2H2O

Molecular weight: 512.9

Chemical Structure: 


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Product Name

Doxycycline hyclate

Shelf Life

2 years

Packing

25kg/drum

Specification

BP/USP/EP

Items

Standard

Appearance

Yellow crystalline powder

Solubility

Freely soluble in water and in methanol, sparingly soluble in ethanol(96 per cent).It dissolves in solutions of alkali hydroxides and carbonates.

Identification

a)HPLC

b)Sulphuric acid reaction a yellow colour develops

c)It gives reaction of chlorides

pH

2.0~3.0

Specific Absorbance

At 349nm E.(1%) is 300~335

Specific optical rotation

-120°~-105°

Heavy metals

≤50ppm

Light-absorbing impurities

At 490nm≤0.07

6-epidoxycycline

≤2.0%

metacycline

≤2.0%

4-epidoxycycline

≤0.5%

4-epi-6-epidoxycycline

≤0.5%

oxytetracycline

oxytetracycline

2-acety-2-decarbamoyldoxycycline ADOT

≤0.5%

Any other impurity

≤0.5%

Ethanol

4.3~6.0%(m/m)

Sulphated ash

≤0.4%

Water

1.4~2.8%

Assay(C22H25CIN2O8)

95.0%~102.0%

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    Add:20Floor ,B Block.Building 1,Pharma valley,high-tech zone,jinan,Shandong
    Tel:+86-531-87100375
    Fax:+86-531-87105371
    Ph:+8613964066237
    E-mail:chenli@amfoodchem.com
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